Publications

Publications

Journal Article:

  • Andrieu, J., Re, F., Russo, L., Nicotra, F. Phage-displayed peptides targeting specific tissues and organs, Journal of Drug Targeting, 24 Oct 2018,Doi: 10.1080/1061186X.2018.1531419

  • Bisso S., Degrassi A., Brambilla D., Leroux J.-C., “Poly(Ethylene Glycol)-Alendronate Coated Nanoparticles for Magnetic Resonance Imaging of Lymph Nodes”, J Drug Target 2018;1–11, Doi: 10.1080/1061186X.2018.1545235

  • B. Loretz, N. Schneider-Daum, M. Windbergs, U. Schäfer, M. Schneider, C.-M. Lehr. Barriers and motivations for non-invasive drug delivery. Editorial for the Biological Barrier Special Issue in European Journal of Pharmaceutics and Biopharmaceutics. September 2017, 118, pp:1-2 doi: 10.1016/j.ejpb.2017.04.016

  • Cox A, et al. Evolution of nanoparticle protein corona across the blood-brain barrier. ACS Nano, 2018, 12:7292-7300. Doi: 10.1021/acsnano.8b03500

  • Dasgupta A., Liu M., Ojha T., Storm G., Kiessling F., Lammers T. “Ultrasound-mediated drug delivery to the brain: principles, progress and prospects”, Drug Discovery Today: Technologies, 2016 Jun; 20: 41–48, doi: 10.1016/j.ddtec.2016.07.007

  • Ho, D.-K., Frisch, S., Biehl, A., Terriac, E., De Rossi, C., Schwarzkopf, K., Lautenschläger, F., Loretz, B., Murgia, X., Lehr, C.-M. Farnesylated Glycol Chitosan as a Platform for Drug Delivery: Synthesis, Characterization, and Investigation of Mucus-Particle Interactions. (2018) Biomacromolecules, 19 (8), 3489-3501. Doi: 10.1021/acs.biomac.8b00795

  • Ho, D.-K., Costa, A., De Rossi, C., De Souza Carvalho-Wodarz, C., Loretz, B., Lehr, C.-M. Polysaccharide Submicrocarrier for Improved Pulmonary Delivery of Poorly Soluble Anti-infective Ciprofloxacin: Preparation, Characterization, and Influence of Size on Cellular Uptake. (2018) Molecular Pharmaceutics, 15 (3), 1081-1096. Doi: 10.1021/acs.molpharmaceut.7b00967

  • T.Benjamin, M.Baues, T. Ojha, D.Möckel, S.Koyadan V., J. Steitz, L.van Bloois, G. Storm, F. Kiessling, T. Lammers. "Sonoporation enhances liposome accumulation and penetration in tumors with low EPR." Journal of Controlled Release (02.2016) 30074-8.

  • T., Okan, T. Ojha, G. Storm, F.Kiessling, T. Lammers. "Targeting cellular and microenvironmental multidrug resistance." (2016): 1199-1202.

  • M. Colombo, L. Fiandra, G. Alessio, S. Mazzucchelli, M. Nebuloni, C. De Palma, K. Kantner, B. Pelaz, R. Rotem, F. Corsi, W.J. Parak, D. Prosperi. Tumour homing and therapeutic effect of colloidal nanoparticles depend on the number of attached antibodies. Nature Commun. 2016 DOI: 10.1038/ncomms13818. 

  • Saraiva, S. M., Castro-López, V., Pañeda, C., Alonso, M. J.;„Synthetic nanocarriers for the delivery of polynucleotides to the eye”., European Journal of Pharmaceutical Sciences,2017, 103, 5-18DOI: 10.1016/j.ejps.2017.03.001

  • Lazzari G., Couvreur P., Mura S.; ”Multicellular tumor spheroids: a relevant 3D model for the in vitro preclinical investigation of polymer nanomedicines”; Polymer Chemistry; 2017; DOI: 10.1039/c7py00559h

  • Lazzari G.,Nicolas V., Matsusaki M., Akashi M., Couvreur P., Mura S. Multicellular spheroid based on a triple co-culture: A novel 3D model to mimic pancreatic tumor complexity. Acta Biomater., 15 Sept 2018, 78, 296-307. Doi: 10.1016/j.actbio.2018.08.008.

  • Sun Q, Ojha T, Kiessling F, Lammers T, Shi Y.” Enhancing Tumor Penetration of Nanomedicines”. Biomacromolecules. 2017 Mar 31; 18(5):1449-59. doi: 10.1021/acs.biomac.7b00068.

  • Lazzari G., Couvreur P., Mura S.; ”Multicellular tumor spheroids: a relevant 3D model for the in vitro preclinical investigation of polymer nanomedicines”; Polymer Chemistry; 2017. Doi : 10.1039/c7py00559h

  • Ojha T, Pathak V, Shi Y, Hennink WE, Moonen CT, Storm G, Kiessling F, Lammers T. “Pharmacological and physical vessel modulation strategies to improve EPR-mediated drug targeting to tumors”. Advanced Drug Delivery Reviews. 2017 Jul 8. Doi: 10.1016/j.addr.2017.07.007

  • Ojha T,Pathak V, Shi Y, Hennink WE, Moonen CT, Storm G, Kiessl ing F, Lammers T. “Pharmacological and physical vessel modulation strategies to improve EPR-mediated drug targeting to tumors”. Advanced Drug Delivery Reviews. 8 July 2017, S0169-409X(17) pp: 30104-7, doi : 10.1016/j .addr.2017.07.007

  • Santalices I., Gonella A., Torres D., Alonso MJ, “Advances on the formulation of proteins using nanotechnologies”, Journal of Drug Delivery Science and Technology, 2017, 42, 155-180. Doi: 10.1016/j.jddst.2017.06.018

  • Saraiva, S. M., Castro-López, V., Pańeda, C., Alonso, M. J.; Synthetic nanocarriers for the delivery of polynucleotides to the eye”. European Journal of Pharmaceutical Sciences, 2017, 103, 5-18. Doi : 10.1016/j .ejps.2017.03.001

  • Sun Q, Ojha T, Kiessling F, Lammers T, Shi Y.” Enhancing Tumor Penetration of Nanomedicines”. Biomacromolecules. 2017 Mar 31; 18(5):1449-59. Doi: 10.1021/acs.biomac.7b00068

  • Yasar, H., Ho, D.-K., De Rossi, C., Herrmann, J., Gordon, S., Loretz, B., Lehr, C.-M. Starch-chitosan polyplexes: A versatile carrier system for anti-infectives and gene delivery. (2018) Polymers, 10 (3), art. no. 252. Doi:10.3390/polym10030252;

  • Vinciguerra D., Tran J., Nicolas J., Telechelic polymers from reversible-deactivation radical polymerization for biomedical applications”, Chem. Commun., 2018, 54, 228-240. Doi: 10.1039/C7CC08544C

  • Vinciguerra D., Denis S., Mougin J., Jacobs M., Mura S., Guillaneuf Y., Couvreur P., Nicolas J., A Facile Route to Heterotelechelic Polymer Prodrug Nanoparticles for Imaging, Drug Delivery and Combination Therapy”. J. Control. Release, 2018, 286, 425-438. Doi: 10.1016/j.jconrel.2018.08.013

      Book section/chapter

  • Avvakumova S., Colombo M., Galbiati E., Mazzucchelli S., Rotem R. and Prosperi D., Chapter name: “Bioengineered Approaches for Site Orientation of Peptide-Based Ligands of Nanomaterials”Book name: “Biomedical applications of functionalized nanomaterials” (by Bruno Sarmento and Jose das Neves) Publication: Elsevier Pages 139-170, ISBN: 978-0-323-50878-0

Manuscripts: 

  • SantalicesI., Gonella A, Torres D, Alonso M.J.; „Technological advances on the formulation of proteins using nanotechnologies” Journal of Drug Delivery Science and Technology,.In press.

  • Yasar H., Ho D.K., De Rossi C, Herrmann J., Gordon S., Loretz B., Lehr C.M.; "Starch-chitosan polyplexes: a versatile carrier system for anti-infectives and gene delivery"Molecular Pharmaceutics, submitted manuscript

  • Santalices I., Gonella A., Torres D., Alonso M.J.; "Advances in the formulation of proteins using nanotechnologies".  Journal of Drug Delivery and Technology, In Press.

 

Poster and oral presentations of the ESRs:

  • Lazzari,G.; Mura, S. ; Couvreur, P. Shedding lights on cancer cells and their microenvironment: in vitro 3D tumor model of pancreatic cancer for preclinical prediction of in vivo behavior of nanomedicines. XVIe Journèe de l’Ecole Doctorale “Innovaation Thérapeutique: du fondamental à l’appliqué”, Faculté de Pharmacie, Châtenay-Malabry, June  17, 2016 (Poster presentation)

  • Lazzari,G.; Mura, S.; Couvreur, P. Shedding lights on cancer cells and their microenvironment: in vitro 3D tumor model of pancreatic cancer for preclinical prediction of in vivo behavior of nanomedicines. Doc&PostDoc Day, Institute Galien UMR-8612, Orsay, June  20, 2016 (Poster presentation)

  • T. Ojha ’Priming tumor blood vessels and the tumor microenvironment to improve nanomedicine-mediated drug delivery’. 11th European Molecular Imaging meeting (EMIM 09.03.2016) in Utrecht (Netherlands). (Poster and oral presentation) 

  • T. Ojha ’Priming tumor blood vessels and the tumor microenvironment to improve nanomedicine-mediated drug delivery’. CLINAM conference in Basel and WMIC conference in New York. (Poster presentation)

  • S. Bisso, Brambilla D., Leroux J.-C., Calcium phosphate nanoparticles for the dual delivery of bisphosphonates and siRNA to cancer cells, 4th Bilateral ETH-Chalmers Workshop, ETH Hönggerberg, Zurich (CH). September 19-21, 2016. (Poster presentation)

  • Vinciguerra, D.; Couvreur, P.; Nicolas, J.Synthesis and evaluation of Dual-Functionalized polymer prodrug nanoparticles for anticancer therapy XVIe Journèe de l’Ecole Doctorale “Innovaation Thérapeutique: du fondamental à l’appliqué”, Faculté de Pharmacie, Châtenay-Malabry, June  17, 2016 (Poster presentation)

  • Vinciguerra, D.; Couvreur, P.; Nicolas, J. Synthesis and evaluation of Dual-Functionalized polymer prodrug nanoparticles for anticancer therapy Doc&PostDoc Day, Institute Galien UMR-8612, Orsay, June  20, 2016 (Poster presentation)

  • R. Edwards, F. Nicotra, B. La Ferla. Nanobiotechnologies for preclinical studies Glyconanoparticles for drug targeting and delivery BtBsDay2015 Abstract 1-15

  • R. Edwards, F. Nicotra, B. La Ferla Novel Therapeutic Opportunities using Glyconanoparticles for Carbohydrate specific intracellular Delivery XV Convegno-Scuola sulla Chimica dei Carboidrati Certosa di Pontignano , 19-22 JUNE 2016

  • Khiet Ho-Duy*,Hanzey Yasar*, Chiara De Rossi, Sarah Gordon, Brigitta Loretz and Claus-Michael Lehr. ‘Starch-Chitosan polyplexes as a versatile drug delivery platform with tunable release characteristics’. 6th HIPS Symposium, Recent Developments in Infection Research, Saarbrücken, June 29th, 2016 ((*) Co-first authors) (Poster presentation)

  • Xabi Murgia, Duy-Khiet Ho, Brigitta Loretz, Konrad Schwarzkopf, Ulrich Friedrich Schaefer, and Claus-Michael Lehr. ‘Nanoparticle transport through human undiluted tracheal mucus’. CLINAM European Foundation for Clinical Nanomedicine, June 26-29, 2016, Basel (Poster presentation)

  • Hanzey Yasar, Khiet Ho-Duy, Chiara De Rossi, Sarah Gordon, Brigitta Loretz and Claus-Michael Lehr. ‘Starch-Chitosan polyplexes as a novel, versatile drug carrier system for transfollicular vaccination’. GPEN2016, November 9-12, 2016 at the University of Kansas. (Poster presentation)

  • A. Cox,S. Mancini, L. Calabresi, F. Re, Exploiting physiological proteins to boost the Aβ clearance from the brain: implication for Alzheimer’s disease therapy, XIV FISV Congress, September 2016,  Rome, Italy

  • F. Re , A. Cox, Exploiting physiological proteins to enhance the blood-brain barrier crossing of nanoparticles. Workshop of the Italian Society of Biochemistry: New Frontiers of Biological Membranes, May 2016 Milan, Italy

  • Ho D.K, Martins Maia da Costa A.M., De Rossi C., de Souza Carvalho-Wodarz C., Loretz B, Lehr C.M.; ‘Polysaccharide Sub-Microcarrier for Anti-infectives Delivery. 13th Zsigmondy colloquium, April 5-7, 2017 at INM, Saarbrücken, Germany. poster presentation

  • Ho D.K, Yasar H., Martins Maia da Costa A.M., De Rossi C., Herrmann J, de Souza Carvalho-Wodarz C., Loretz B, Lehr C.M.; “Polysaccharides based Versatile Nano-carriers for Pulmonary Anti-infectives Delivery”. 44th Annual Meeting & Exposition of the Controlled Release Society, July 16-19, 2017, Boston, Massachusetts, U.S.A. poster presentation

  • Ho D.K,; Costa A, De Rossi C., de Souza Carvalho-Wodarz C., Loretz B., Lehr, C.M.; “Pulmonary Targeted Anti-infectives Delivery System of Chitosan-Cyclodextrin Based sub-MicroCarriers”. 7th HIPS Symposium on pharmaceutical sciences devoted to infection research, June 29, 2017, Saarbrucken, Germany. poster presentation

  • Ho D.K,; Costa A, De Rossi C., de Souza Carvalho-Wodarz C., Loretz B., Lehr, C.M.; ‘Versatile Polysaccharide Sub-Micro Coacervate for Antibiotics Delivery’. 21st Annual Meeting of The Controlled Release Society Germany Local Chapter, March 2-3, 2017, Marburg, Germany, poster presentation

  • Murgia X, Ho D.K, Loretz B., Friedrich Schaefer U., Lehr, C.M.; “Addressing the size-dependent mobility of nanoparticles through human tracheal mucus”. 21st Annual Meeting of The Controlled Release Society Germany Local Chapter, March 2-3, 2017, Marburg, Germany, poster presentation

  • Montefusco-Pereira C.V., Carvalho-Wodarz C., Lehr, C.M. “Growth of P. aeruginosa on a 3D Model of Cystic Fibrosis Bronchial Epithelia and Macrophages” COMPACT (IMI project) Scientific annual meeting, March 22-24, 2017, Saarbrücken, Germany, poster presentation

  • Ho D.K,; Costa A, De Rossi C, de Souza Carvalho-Wodarz C., Loretz B., Lehr, C.M. "Pulmonary Targeted Anti-infectives Delivery System of Chitosan-Cyclodextrin Based sub-MicroCarriers", HIPS Symposium June 29th, 2017. Poster presentation:

  • Ho D.K., Yasar H., Costa A., De Rossi C., Herrmann J., de Souza Carvalho-Wodarz C., Loretz B.,  Lehr C.M.; "Polysaccharides based versatile carriers for pulmonary anti-infectives delivery",44th Controlled Release Society (CRS) conference, July 16-19, 2017. Poster presentation:

  • Lazzari G., Mura S., Couvreur P.; ”Shedding lights on cancer cells and their microenvironment: in vitro 3D tumor model of pancreatic cancer for preclinical prediction of in vivo behavior of nanomedicines”; Doc & PostDoc Day 2017 of Institut Galien Paris-Sud, University Campus of Orsay (France), 9th June 2017, oral presentation

  • Bisso S.;“Calcium phosphate nanoparticles for the dual delivery of bisphosphonates and pDNA”, Swiss Pharma Science Day, Bern (CH), 22 August 2017. abstract and poster presentation

  • Colombo M.;"How the number of antibodies attached to colloidal nanoparticles affect tumour targeting and therapeutic effect? NanoInnovation 2017- Rome (Italy), September 26-29, 2017, oral presentation

  • Prosperi D.; "Dependence of in vivo tumor homing, localization and therapeutic effect of colloidal nanoparticles on the number of attached antibodies"- 15th World Medical Nanotechnology Congress, Osaka (Japan), October 18-19, 2017, oral presentation

  • Alonso M.J.; „La nanomedicina en terapias oculares” III Simposio Internacional Biomateriales y Superficie Ocular: Lentes de Contacto, 31 March 2017, Valencia, Spain, oral presentation

  • Alonso M.J.; „Nanocarriers that help drugs overcoming the corneal barrier.”  30 Years of Drug Delivery Research In Honour of Arto Urtti’s, June 2017, Kuopio, Finland, oral presentation

  • Alonso M.J.; „Formulation of biologicals using nanotechnology approaches”, International Conference on Nanomedicine and Nanobiotechnology  25-26 September 2017, Barcelona, Spain, oral presentation 

  • Bisso S., Brambilla D., Castagner B., Leroux J.-C., “Calcium phosphate nanoparticles for the dual del ivery of bisphosphonates and pDNA”, 12th International Conference and Workshop on Biological Barriers, 27 – 29 August 2018, Saarbrücken, Germany. (Oral presentation).

  • Bisso S., Brambilla D., Castagner B., Leroux J.-C., “Calcium phosphate nanoparticles for the dual del ivery of bisphosphonates and pDNA” , Doktorandentag Autumn Session 2018, Institute of Pharmaceutical Sciences, Department of Chemistry and Applied Biosciences, 12 September 2018, ETH Zurich. (Oral presentation).

  • Bisso S., Brambilla D., Castagner B., Leroux J.-C., “Calcium phosphate nanoparticles for the dual del ivery of bisphosphonates and pDNA”, the Global ization of Pharmaceutics Education Network (GPEN) conference, National University of Singapore, 26 – 29 September 2018, Singapore. (Poster presentation).

  • Edwards R. “New procedure and l inkers for liposomes” XXXVIII National conference of the organic chemistry division of the Italian chemical society (09/09/2018 – 13/09/2018) Milano, Italy (Poster Presentation)

  • Edwards R.“New procedure for liposomes Glyco-functionalization” Biobarriers 2018: 12th international conference and workshop on biological barriers (Saarbrucken, Germany) – Oral and Poster Presentations

  • Andrieu, J., Cox, A., Nicotra, F., Masserini M., Re F., and Russo L. Phage displayed brain targeting peptides. Poster presented at: BtBsday – Giornata del Dipartimento di Biotecnologie e Bioscienze, University of Mi lano-Bicocca, Italy, 13 December 2017

  • Andrieu, J., Russo, L., and Nicotra, F. Phage-displayed brain-targeting peptides. Poster presented at: 12th International conference and workshop on biological barriers (BioBarriers), Saarbrücken, Germany, 27-29 August 2018. (Oral presentation)

  • Andrieu J., Barbugian F., Nicotra F., Masserini M., Re F., Russo L., Liposome functionalisation with phage-displayed brain-targeting peptides. Poster presented at: 38th Convegno Nazionale del la Divisione di Chimica Organica del la Società Chimica Italiana, Mi lan, Italy, 9-13 September 2018

  • Lazzari G., Mura S., Couvreur P.; Shedding lights on cancer cells and their microenvironment: in vitro 3D tumor model of pancreatic cancer for preclinical prediction of in vivo behavior of nanomedicines; Journée de la Recherche 2017, Université Paris-Sud (France), 24th November 2017 (oral presentation)

  • Lazzari G., Mura S. and Couvreur P.; Multicellular spheroid based on a triple coculture: a novel 3D model to mimic pancreatic tumor complexity; Drug Discovery and New Therapeutics – International symposium, University campus of Orsay (France) , 9-11th April 2018. (oral presentation)

  • Lazzari G., Nicolas V., Matsusaki M., Akashi M., Couvreur P., Mura S.; Multicellular spheroid based on a triple co-culture: a novel 3D model to mimic pancreatic tumor complexity; BioBarriers 2018 - the 12th International Conference and Workshop on Biological Barriers, Saarbrücken (Germany), 27-29th August 2018 (oral presentation)

  • Lazzari G., Mura S., Couvreur P.; Shedding lights on cancer cells and their microenvironment: in vitro 3D tumor model of pancreatic cancer for preclinical prediction of in vivo behavior of nanomedicines; Journée de la Recherche 2017, Université Paris-Sud (France), 24th November 2017 (poster presentation)

  • Lazzari G., Mura S., Couvreur P.; Shedding lights on cancer cells and their microenvironment: in vitro 3D tumor model of pancreatic cancer for preclinical prediction of in vivo behavior of nanomedicines; Tumour Models Summit 2017, London (United Kingdom), 6-7th December 2017. (poster presentation)

  • Lazzari G., Mura S., Couvreur P.; Shedding lights on cancer cells and their microenvironment: in vitro 3D tumor model of pancreatic cancer for preclinical prediction of in vivo behavior of nanomedicines; XI I Spanish-Portuguese Conference on Controlled Drug Delivery, University of Coimbra, 14-16th January 2018. (poster presentation)

  • Lazzari G., Mura S., Couvreur P.; Shedding lights on cancer cells and their microenvironment: in vitro 3D tumor model of pancreatic cancer for preclinical prediction of in vivo behavior of nanomedicines; Journées thématiques GDR Imabio Imagerie fonctionnel le des organoďdes, Toulouse (France), 29-30th Mars 2018. (poster presentation)

  • Montefusco-Pereira C.V.,Carvalho-Wodarz C., Lehr C-M. 3D in vitro model of the cystic fibrosis infected upper airways: host-pathogen interaction, drug efficacy and inflammation. Biobarriers, 27-29 August 2018. Saarbrücken, Germany. (poster presentation)

  • Montefusco-Pereira C.V.,Horstmann J, Maurer C.K. , Empting M. , Hartmann R.W. , Schneider-Daum N. , Carvalho-Wodarz C. , Lehr C-M. ; Co-culture of cystic fibrosis human bronchial epithelia and macrophages to evaluate host response: quorumsensing and cytokines release. 8th HIPS Symposium on pharmaceutical sciences devoted to infection research, June 14, 2018. Saarbrücken, Germany. (poster presentation)

  • Montefusco-Pereira C.V.,Carvalho-Wodarz C., Lehr C-M.; Co-culture of human cystic fibrosis bronchial epithelia cells and macrophages to study host-pathogen interactions in P. aeruginosa infection. EMBL Innate Immunity in Host-Pathogen Interactions, 24 - 27 June 2018. Heidelberg, Germany. (poster presentation)

  • Montefusco-Pereira C.V., Carvalho-Wodarz C., Lehr C-M.; Co-culture of cystic fibrosis human bronchial epithe ia and macrophages to evaluate host-responses and efficacy of anti-infective formulations on P. aeruginosa infection. XII Spanish- Portuguese Conference on Controlled Drug Delivery: Tailoring drug delivery systems to the patients’ needs, 14-16 January, 2018. Coimbra, Portugal (poster presentation)

  • Montefusco-Pereira C.V., Formicola B., Russo L., Re F., Carvalho-Wodarz C., Schneider-Daum N., Loretz B., Masserini M., Nicotra F., Lehr C-M.; Cationic amino liposomes as proposal for broad spectrum formulation against bacteria adherence and biofilm treatment. BtBsDay 2017, Giornata del Dipartimento di Biotecnologie e Bioscienze – UNIMIB. Milan, December 17th, 2017. (poster presentation)

  • Ho D-K., Desmaele D., Hüfner de Mel lo Martins A.G., De Rossi C., Koch M., Empting M., Hartmann R.W., Loretz B., Couvreur P. and Lehr C-M. ; Squalenyl Hydrogen Sulfate Nanocarrier for Dual-Del ivery of Anti-infective Quorum Sensing Inhibitor and Aminoglycoside Antibiotic Tobramycin XII Spanish-Portuguese Conference on Controlled Drug Del ivery, University of Coimbra, 2018 (oral presentation)

  • Ho D-K., Desmaele D., Hüfner de Mello Martins A.G., De Rossi C., Koch M., Empting M., Hartmann R.W., Loretz B., Couvreur P. and Lehr C-M.; Quorum sensing inhibitor and aminoglycoside antibiotic dual-loaded nano-assemblies as complementary therapy against Pseudomonas aeruginosa infection 12th International Conference and Workshop on Biological Barriers, 27.-29. August 2018, Saarbrücken, Germany (oral presentation)

  • Ho D-K., Desmaele D., Murgia X., Hüfner de Mel lo Martins A.G., De Rossi C., Koch M., Empting M., Hartmann R.W., Loretz B., Couvreur P. and Lehr C-M.; Squalenyl Hydrogen Sulfate based Dual-Delivery Platform for Complementary Therapy of a Novel Alkylquinolone Quorum Sensing Inhibitor and Tobramycin Against Pseudomonas aeruginosa Biofilm, HIPS Symposium June 4, 2018 in Saarbrücken, Germany (poster presentation)

  • Ho D-K., Desmaele D., Murgia X. Hüfner de Mel lo Martins A.G., De Rossi C., Koch M., Empting M., Hartmann R.W., Loretz B., Couvreur P., Lehr C-M.; Increasing Pseudomonas aeruginosa Biofilm Eradicating Efficacy by Dual- Delivery of a Novel Alkylquinolone Quorum Sensing Inhibitor and Tobramycin using Squalenyl Hydrogen Sulfate Nanocarrier, Controlled Release Society Annual Meeting & Exposition, July 22.24, 2018, New York, NY, USA, 2018 (poster presentation)

  • Biehl A., Ho D-K., Frisch S., Loretz B., Schwarzkopf K., Murgia X., Lehr C-M.; ‘Investigating nanoparticle-based drug delivery systems and mucus interaction with Profor MPTA (Protocol for Multiple Particle Tracking Analysis)’. 12th International Conference and Workshop on Biological Barriers. August 27-29, 2018, Saarbrücken, Germany. (poster presentation)

  • Frisch S., Ho D-K., Biehl A., De Rossi C., Loretz B., Murgia X., Lehr C-M., ‘Nanoparticle Tracking Analysis (NTA): a Facile Method for Addressing Nanoparticles and Mucin Glycoproteins Interaction’, 12th International Conference and Workshop on Biological Barriers. August 27-29, 2018, Saarbrücken, Germany. (poster presentation)

  • Biehl A., Ho D-K., Frisch S., Loretz B., Schwarzkopf K., Terriac E., Murgia X., Lehr C-M.; ‘Applying multiple particle tracking to pharmaceutical research: a computational toolbox to address the transport and diffusion of nanoparticles through mucus’ 11th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology. March 19-22, 2018, Granada, Spain. (poster presentation)

  • Loretz B., Ho D-K., Barthold S., Menina S., Gordon S., Lehr C-M.; ‘Carrier technologies for local delivery of anti-infectives’. 11th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology. March 19-22, 2018, Granada, Spain. (poster presentation)

  • Frisch S., Ho D-K., Biehl A., De Rossi C., Loretz B., Murgia X., Lehr C-M., ‘Investigating the Interaction between Nanoparticles and Mucin Glycoproteins by Nanoparticle Tracking Analysis’ . 22nd annual meeting German Controlled Release Society Local Chapter. March 01-02, 2018, Hal le, Germany. (poster presentation).

  • Biehl A., Ho D-K., Frisch S., Loretz B., Schwarzkopf K., Lehr C-M., Murgia X.; ‘Profor MPTA -Protocol for Multiple Particle Tracking Analysis: A toolbox to address the behaviour of nanoparticle-based drug delivery systems in mucus. 22nd annual meeting German Controlled Release Society Local Chapter. March01-02, 2018, Hal le, Germany. (poster presentation)

  • Vinciguerra D.,Denis S., Jacobs M., Mura S., Guillaneuf Y., Couvreur P., Nicolas J., Heterotelechelic polymer prodrug nanoparticles for anticancer therapy. Bordeaux Polymer Conference, Bordeaux, France, 28-31. May, 2018 (oral presentation)

  • Vinciguerra D., Denis S., Jacobs M., Mura S., Guillaneuf Y., Couvreur P., Nicolas J., "Heterotelechelic polymer prodrug nanoparticles for anticancer therapy”. ,XVIIeme Journée de l ’Ecole Doctorale, ITFA (ED569) , Chatenay-Malabry, France 22 June, 2018 (oral presentation)

  • Vinciguerra D., Bao Y., Couvreur P., Nicolas J., “The drug-initiated method: a convenient way to formulate polymer nanoparticles for anticancer therapy”, JDR 2017, Chatenay-Malabry, France, 24 November, 2017 (poster presentation)

  • Vinciguerra D., Couvreur P., Nicolas J. “Synthesis and evaluation of heterotelechelic polymer prodrug nanoparticles for anticancer therapy”. XII Spanish-Portuguese Conference on Controlled Drug Del ivery, Coimbra, Portugal, 16-17 January 2018 (poster presentation)

  • Vinciguerra D., Denis S., Jacobs M., Mura S., Guillaneuf Y., Couvreur P., Nicolas J. “Heterotelechelic polymer prodrug nanoparticles for anticancer therapy”., Bordeaux Polymer Conference, Bordeaux, France, 28-31 May 2018 (poster presentation)

  • Vinciguerra D., Denis S., Jacobs M., Mura S., Guillaneuf Y., Couvreur P., Nicolas J., “Heterobifunctional anticancer polymer prodrug nanoparticles for combination therapy”. BioBarrier 2018, Saarbruken, Germany, 27-29 August 2018 BEST POSTER AWARD (poster presentation)

  • Saraiva S.M., Torres D., Alonso M.J., “Development of nanocarriers for intracellular delivery of protein drugs.” XII Spanish-Portuguese Conference Controlled Drug Delivery, Coimbra, 14-17 January 2018 (poster presentation)

  • Gonella A., Torres D., Alonso M.J., “A novel hyaluronic acid based nanocarrier for encapsulating proteins” 12th International Conference and Workshop on Biological Barriers (BioBarriers 2018) , Saarbruken, 27-30 August 2018

  • Ho D.K, Martins Maia da Costa A.M., De Rossi C., de Souza Carvalho-Wodarz C., Loretz B, Lehr C.M.; ‘Polysaccharide Sub-Microcarrier for Anti-infectives Delivery’, 13th Zsigmondy colloquium, April l 5-7, 2017 at INM, Saarbrücken, Germany. poster presentation

  • Ho D.K, Yasar H., Martins Maia da Costa A.M., De Rossi C., Herrmann J, de Souza Carvalho-Wodarz C., Loretz B, Lehr C.M.; “Polysaccharides based Versatile Nanocarriers for Pulmonary Anti-infectives Delivery”. 44th Annual Meeting & Exposition of the Controlled Release Society, July 16-19, 2017, Boston, Massachusetts, U.S.A. poster presentation

  • Ho D.K,; Costa A, De Rossi C., de Souza Carvalho-Wodarz C., Loretz B., Lehr C.M.; “Pulmonary Targeted Anti-infectives Delivery System of Chitosan-Cyclodextrin Based sub-MicroCarriers”, 7th HIPS Symposium on pharmaceutical sciences devoted to infection research, June 29, 2017, Saarbrucken, Germany. poster presentation

  • Ho D.K, Costa A, De Rossi C., de Souza Carvalho-Wodarz C., Loretz B., Lehr C.M.; ‘Versatile Polysaccharide Sub-Micro Coacervate for Antibiotics Delivery’. 21st Annual Meeting of The Controlled Release Society Germany Local Chapter, March 2-3, 2017, Marburg, Germany, poster presentation

  • Murgia X, Ho D.K, Loretz B., Friedrich Schaefer U., Lehr C.M.; “Addressing the size-dependent mobility of nanoparticles through human tracheal mucus”. 21st Annual Meeting of The Controlled Release Society Germany Local Chapter, March 2-3,2017, Marburg, Germany, poster presentation

  • Montefusco-PereiraC.V., Carvalho-Wodarz C., Lehr, C.M. “Growth of Paeruginosa on a 3D Model of Cystic Fibrosis Bronchial Epithelia and Macrophages” COMPACT (IMI project) Scientific annual meeting, March 22-24, 2017, Saarbrücken, Germany, poster presentation

  • Ho D.K, Costa A, De Rossi C, de Souza Carvalho-Wodarz C., Loretz B., Lehr, C.M. "Pulmonary Targeted Anti-infectives Delivery System of Chitosan-Cyclodextrin Based sub-MicroCarriers", HIPS Symposium June 29th, 2017. Poster presentation:

  • Ho D.K., Yasar H., Costa A., De Rossi C., Herrmann J., de Souza Carvalho-Wodarz C., Loretz B., Lehr C.M.;"Polysaccharides based versati le carriers for pulmonary anti-infectives delivery",44th Controlled Release Society (CRS) conference, July 16-19, 2017. Poster presentation

  • Lazzari G., Mura S., Couvreur P.;” Shedding lights on cancer cells and their microenvironment: in vitro 3D tumor model of pancreatic cancer for preclinical prediction of in vivo behavior of nanomedicines”; Doc & PostDoc Day 2017 of Institut Galien Paris-Sud, University Campus of Orsay (France), 9th June 2017, oral presentation

  • Bisso S.;“Calcium phosphate nanoparticles for the dual del ivery of bisphosphonates and pDNA”, Swiss Pharma Science Day, Bern (CH), 22 August 2017, abstract and poster presentation

  • Ojha T., “Priming the tumor blood vessels and microenvironment with liposomal corticosteriod to improve nanomedicine mediated drug delivery”, Mobi 2017 Aachen (Conference for Imaging) November 23-24, oral presentation

  • Ojha T., “Priming the tumor blood vessels and microenvironment with liposomal corticosteriod to improve nanomedicine mediated drug delivery”, Biobarriers international conference, Saarbrucken 2018, 27-29 August, oral presentation

  • Cox. A,Oral & Poster Presentation: Biobarriers, Saarbrucken, Aug 27-29th 2018.

  • Cox. A, Poster presentation: Workshop – Interaction between nanomaterials and the immune system: medical exploitations and safety issues, Milan, Jul 9-10th 2018.

  • Cox. A,Oral Presentation: Evolution of the Protein Corona across the Blood-Brain Barrier. National PhD Meeting, Salerno, Italy, Mar 22-24th 2018.

  • Cox. A, Poster PC-55: Nanoparticles for Therapy and Diagnosis of Neurodegenerative Diseases. XII Spanish-Portuguese Conference on Controlled Drug Delivery, Coimbra, Jan 14-16th 2018.

      Outreach activity

  • Khiet Duy Hodid an oral presentation of the NABBA project during a visit of a Korean visitors group from Ewha Womans University, Pharmacy department (group of 1 Professor und 12 students from 1st or 2nd year pharmacy study finished.) to our Department.

  • Khiet Duy Hoparticipated in the MCAA General Assembly: Venice, 4-5 March 2016.

  • Rana EdwardsPress interview: La Repubblica Milano 01/10/2016- Page 1+7-Meet me Tonight Corriere della Sera Milano 03/10/2016 – Quotidiano- Page 1+3 Università degli Studi di Milano – Bicocca-Press office YouTube interview Dec 2, 2015

  • European Researcher’s night: Biotalentum as partner organisation took part in the European Researchers’ Night and had a poster introducing NABBA project.

  •  Daniele Vinciguerra and Rana Edwards took part in MeetMeTonight and presented their work.

  • Carlos Montefuscoattended the Summer School Molecular Medicine from the Interdisciplinary Center for Clinical Research of the University Hospital of Jena from August to September 2015.

  • Carlos Montefuscoattended the European Health Science Match 2016 that occurred at the Heidelberg Life Science Cluster.

  • Ho D.K., Loretz B., Lehr C.M. (inventors),Aminoglycoside derivatives and nano-assemblies thereof, including those with quorum sensing inhibitory functionFiled patent: EP17179011.6

  • Alonso M..J.;“Nanoengineered drug delivery for specialized therapies", 6th FIP Pharmaceutical Sciences World Congress, Stockholm, Sweden, May 2017, Invited Lecture 

  • Ho D.K.;Drug delivery – using nano and micro technologies”, Denmark Technical University. Summer school in PhD Summer School

This project has received funding from the European Union’s HORIZON 2020 Programme for research, technological development and demonstration under grant agreement no. 642028 H2020-MSCA-ITN-2014